| LIGA CONCACAF 2021 | ||||
| Ronda Preliminar | ||||
| 3-ago-2021 | Ciudad | Santa Lucia | 3 | Osorio, De Leon, Acuņa |
| de Guatemala | Metropolitan | 0 | ||
| 17-ago-2021 | Bayamon | Metropolitan | 1 | Maldonado |
| Santa Lucia | 2 | Acuņa, Guay | ||
| 3-ago-2021 | Managua | Diriangen | 0 | |
| Marathon | 1 | Martinez | ||
| 18-ago-2021 | San Pedro Sula | Marathon | 2 | Lopez, Arriaga |
| Diriangen | 1 | Mosquera | ||
| 5-ago-2021 | Belmopan | Verdes | 0 | |
| Santos de Guapiles | 1 | Mora | ||
| 18-ago-2021 | San Jose | Santos de Guapiles | 5 | Paradela, Rodriguez (2, 1P), Lopez, Myvette (A) |
| Verdes | 1 | Fajardo | ||
| 5-ago-2021 | Ciudad | Comunicaciones | 1 | Larin |
| de Guatemala | Once Deportivo | 1 | Medrano | |
| 19-ago-2021 | San Salvador | Once Deportivo | 0 | |
| Comunicaciones | 3 | Contreras (P), Lacayo, Lezcano (P) | ||
| 12-ago-2021 | San Salvador | Forge | 3 | Borges, Babouti, Choiniere |
| FAS | 1 | Flores | ||
| 17-ago-2021 | San Salvador | FAS | 2 | Reyes, Torres |
| Forge | 2 | Navarro, Grant | ||
| Octavos de Final | ||||
| 21-sep-2021 | Ciudad | Guastatoya | 1 | Landin |
| de Guatemala | Alajuelense | 1 | De Lemos (A) | |
| 28-sep-2021 | Alajuela | Alajuelense | 2 | Venegas, Martinez |
| Guastatoya | 2 | Dominguez, Landin | ||
| 21-sep-2021 | Paramaribo | Inter Moengotapoe | 0 | |
| Olimpia | 6 | Bengtson (P), Pineda, Rodriguez, Reyes, Hernandez (2) | ||
| 28-sep-2021 | Tegucigalpa | Olimpia | 3 | WO |
| Inter Moengotapoe | 0 | WO | ||
| 21-sep-2021 | Hamilton | Forge | 0 | |
| Independiente | 0 | Babouli, Bekker | ||
| 28-sep-2021 | Ciudad de Panama | Independiente | 0 | |
| Forge | 2 | Babouli, Bekker | ||
| 22-sep-2021 | Ciudad | Comunicaciones | 2 | Lezcano, Lacayo |
| de Guatemala | Alianza | 1 | Riascos | |
| 29-sep-2021 | San Salvador | Alianza | 0 | |
| Comunicaciones | 1 | Lacayo | ||
| 22-sep-2021 | San Pedro Sula | Marathon | 2 | Martinez (P), Castillo |
| Real Esteli | 0 | |||
| 29-sep-2021 | Esteli | Real Esteli | 2(4) | Farias, Talavera |
| Marathon | 0(5) | |||
| 23-sep-2021 | Ciudad | Santa Lucia | 0 | |
| de Guatemala | Saprissa | 2 | Bolaņos, Waston | |
| 30-sep-2021 | San Jose | Saprissa | 4 | Sinclair, Bolaņos, Torres (P), Barrantes |
| Santa Lucia | 2 | Velasquez, Acuņa | ||
| 23-sep-2021 | San Jose | Santos de Guapiles | 1 | Mendez |
| Plaza Amador | 0 | |||
| 29-sep-2021 | Ciudad de Panama | Plaza Amador | 0 | |
| Santos de Guapiles | 2 | Mason, Mendez | ||
| 23-sep-2021 | Ciudad de Panama | Universitario | 2 | Gonzalez, Triana |
| Motagua | 2 | Lopez (2) | ||
| 30-sep-2021 | Tegicigalpa | Motagua | 1 | Decas (P) |
| Universitario | 0 | |||
| Cuartos de Final | ||||
| 20-oct-2021 | San Jose | Santos de Guapiles | 3 | East, Samuel (A), Lopez |
| Forge | 1 | Bekker | ||
| 2-nov-2021 | Hamilton | Forge | 3 | Browne, Babouli, Navarro |
| Santos de Guapiles | 0 | |||
| 21-oct-2021 | San Jose | Saprissa | 4 | Sinclair, Torres, Guzman, Ramirez |
| Comunicaciones | 3 | Santis (2) | ||
| 3-nov-2021 | Ciudad | Comunicaciones | 2 | Lezcano, Anangono |
| de Guatemala | Saprissa | 1 | Waston | |
| 21-oct-2021 | San Pedro Sula | Marathon | 0 | |
| Motagua | 2 | Auzqui, Klusener | ||
| 2-nov-2021 | Tegucigalpa | Motagua | 2 | Moreira (2) |
| Marathon | 0 | |||
| Semifinales | ||||
| 23-nov-2021 | Ciudad | Guatatoya | 0 | |
| de Guatemala | Comunicaciones | 1 | Lezcano | |
| 30-nov-2021 | Ciudad | Comunicaciones | 2 | Anangono, Lezcano |
| de Guatemala | Guatatoya | 1 | Landin | |
| 24-nov-2021 | Hamilton | Forge | 2 | Navarro, Awuah |
| Motagua | 2 | Lopez, Pereira | ||
| 1-dic-2021 | Tegucigalpa | Motagua | 0 | |
| Forge | 0 | |||
| FINAL | ||||
| 8-dic-2021 | Tegucigalpa | Motagua | 1 | Moreira |
| Comunicaciones | 2 | Aparicio, Anangono | ||
| 14-dic-2021 | Ciudad | Comunicaciones | 4 | Anangono (3), Lacayo |
| de Guatemala | Motagua | 2 | Moreira, Vega | |